Concordia University Wisconsin/Ann Arbor

About Concordia University Wisconsin/Ann Arbor

Concordia University invites applicants to apply for the full- time position of Pharmaceutical Research Sciencist. This position is responsible for managing a research laboratory and for overseeing a range of biochemistry-focused research projects. This includes mentoring students on research projects, designing and performing experiments, assisting with writing manuscripts, and managing lab functions such as maintaining equipment and ordering supplies as needed. This position reports to and requires weekly interaction and meetings with the Director of Technology Transfer, who also holds a position in the Dept. of Pharmaceutical Sciences at Concordia University Wisconsin. Current research projects are focused on drug discovery and development, and specifically: (a) Protein- and cell-based binding studies of estrogen agonists, directed toward developing drugs to treat dementia, (b) Biophysical characterization of fluorescent dithio probes to image oxidative stress, and (c) Enzymatic assay and screening of inhibitors of dual-specificity phosphatase-5 (DUSP-5), to affect angiogenesis. Responsibilities Coordinate research activities of undergraduate and master's students working in a biochemistry and biophysics laboratory. Manage the lab, maintaining equipment and supplies. This includes assisting with filling liquid nitrogen and helium on a 500 MHz NMR spectrometer. Keep lab records. Perform cell-based transcriptional activation assays, enzymatic assays, and fluorescence (TR-FRET and FP) assays to characterize binding affinity of lead molecules to target proteins. Assist in summarizing data for publishing manuscripts and posters. Attend and present at regular lab meetings at Concordia, and at partner institutions, as needed. Wlllingness to work with student and faculty-led spinout companies doing drug and diagnostic development work. Knowledge, Skills and Abilities Strong critical and analytical thinking skills, and a passion for science. Professional communication skills, both written and interpersonal Ability to work independently, multi-task, and prioritize responsibilities Ability to work as a member of a collaborative team Knowledge and skill in the use of computers and Microsoft Office, including Excel, Power Point, Outlook, and Graphing software like Graphpad Knowledge and skill in the area of protein expression in coli, and purification. Knowledge and skill in various enzyme kinetic and biophysical binding assays, especially using fluorescence techniques like TR-FRET and fluorescence polarization. Ideal candidates will also have some familiarity with: HPLC, NMR, and/or in silico protein docking. Knowledge of and commitment to the Christian faith and Concordia University mission Education and Experience A science undergraduate degree is required, an MS degree is preferred. Highly qualified applicants will also have prior experience in performing and publishing peer-reviewed research. Some of the above-mentioned skills can be learned on the job, for exceptional candidates. Compensation and Benefits This is a full-time position. Starting range is dependent upon individual qualifications and experience. Concordia health, disability and retirement plan enrollment is available to full-time employees and their eligible dependents. Tuition benefits are available for employees and their qualified dependents. Equal Opportunity Employer It is the policy of CU to provide equal opportunity to all employees and applicants for employment in accordance with all applicable federal, state, and local laws. The University will not discriminate against or harass any employee or applicant for employment because of race, color, sex, pregnancy, national origin (including ancestry), citizenship status, physical or mental disability, age, marital status, gender, veteran or military status, predisposing genetic characteristics, domestic violence victim status, or any other characteristic protected by federal, state or local laws. However, CU is an institution of the LCMS and, to the extent allowed by law, CU reserves the right to give preference in employment based on religion. In addition, preference in holding certain employment positions is given to ordained or rostered ministers of the LCMS. Based on a religious tenet, CU recognizes only male, LCMS ordained Ministers of the Gospel, but recognizes both male and female LCMS Rostered Ministers of the Gospel. The Human Resources Department has been appointed to manage the equal employment opportunity program, including all equal employment opportunity activities, as required by federal, state and local agencies. If any employee or applicant for employment believes this policy has been violated, he/she must contact the Director of Human Resources. Concordia University is a HLC accredited, co-educational, liberal arts school offering more than 70 undergraduate majors, over 40 master's degree programs, and 4 doctoral programs. There are also a variety of accelerated evening and e-learning programs. Physical Demands/Equipment Concordia is a Lutheran higher education community committed to helping students develop in mind, body and spirit for service to Christ in the Church and in the world

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